Jan 2nd, 2024

In a meta-analysis that compared long-term outcomes in patients suffering from Myocardial Infarction with Non-Obstructed Coronary Arteries (MINOCA) versus those with Myocardial Infarction and Coronary Artery Disease (MI-CAD), data from 16 different studies was included (1). The objective was to analyze and compare the outcomes in these two patient groups. The results indicated that the mortality risk was similar between the two groups, though there were some differences in the incidence of Major Adverse Cardiac Events (MACE). The clinical significance of this study lies in its emphasis on the need for further research into the MINOCA patient group, highlighting the complexities and similarities in outcomes compared to those with MI-CAD​​.

In an observational study that focused on the correlation of the Albumin-corrected Anion Gap (ACAG) with prognosis in patients suffering from Acute Myocardial Infarction (AMI), a cohort of 1783 patients was included (2). The findings revealed a significant association between elevated ACAG levels (greater than 20 mmol/L) and increased mortality at both 30 and 360 days post-AMI. The data indicated that ACAG serves as an independent risk factor for mortality in these patients, underlining its clinical significance as a substantial risk factor for both short-term and long-term mortality following an AMI episode​​.

1. Lu X, Zhu S, Lu Y, Li Y. Long term all-cause mortality after myocardial infarction with non-obstructed vs obstructed coronary artery disease: a meta-analysis of adjusted data. BMC Cardiovasc Disord. 2024;24(1):9.

2. Sheng H, Lu J, Zhong L, Hu B, Sun X, Dong H. The correlation between albumin-corrected anion gap and prognosis inpatients with acute myocardial infarction. ESC Heart Fail. 2024.